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We hypothesize that vardenafil improves cognition. This will be apparent as increased recall/recognition scores in a verbal and pictorial memory task, as well as percentage correct in a spatial memory paradigm.
Isomaltulose reduces the decline in working memory and attention span in older children. This reduction in decline is also seen when lower amounts of isomaltulose are combined with a mix of minerals and vitamins.
Objective of this study is to assess the sensitivity of performance in a number of widely used tests for measuring driver impairment to the dose-effects of alcohol.
We hypothesize that black tea ingestion (approximately 530 mg tea polyphenols) in healthy middle-aged humans will lead to a larger mean forearm blood flow response to acetylcholine (i.e. endothelium-dependent vasodilation) We hypothesize that black…
Statins are able to significantly increase peritoneal fibrinolytic activity.
1. TGC with insulin in continuous tube fed patients is superior to TGC with insulin in regularly fed patients; 2. Vildagliptin as add-on therapy to insulin mediated TGC results in less hypoglycemic episodes compared to placebo.
What is the therapeutical effect of amitriptyline in patients with functional dyspepsia? And have stress-sensitive patients more benefit than NOT stress-sensitive patients.
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Inhalation of rhDNase after airway clearande therapy (ACT) increases the expiratory flow at 25% of the actual forced vital capacity (MEF25) compared to inhalation of rhDNase before ACT.
We expect that aprotinin will be better in reducing blood loss and transfusion requirements compared with tranexamic acid. However, tranexamic acid will be more cost effective and avoid the risk of anaphylactic shock at reexposeure seen with…
The CPC-mouthrinse inhibit 15% less of 'de novo' plaqueformation compared to a placebo and hexitine over a period of 3 days in a non-brushing model.
A nutritional supplement enriched with omega-3 fatty acids has beneficial effects on functional and nutritional parameters and on quality of life (QOL) in NSCLC patients undergoing chemo(radiation)therapy and lung resection, compared to a control…
The present study aims at testing whether the 0.07% CPC-mouthrinse has a potential to inhibit gingival inflammation as compared to a placebo over a 6 month period.
It is hypothesized that the behavioral effect (i.e. slower RT and impaired attention) of a non-sedative antihistamine will be apparent in combination with a Pgp-blocker, but will not be apparent when administered alone. This, because when a non-…
The severity of hazelnut allergy will decrease as an additional effect by birch pollen immunotherapy.
1. Oral anticoagulant control is less stable at a low average intake of vitamin K; 2. As a consequence, a low dose vitamin K supplement results in a more stable anticoagulant effect in patients using vitamin K antagonists (VKA); 3. Dietary intake…
1. What are the normoxic ventilation parameters and systolic PAP in MH patients? 2. What is the influence of hypoxia on the systolic PAP on MH patients?
The primary objective is to investigate whether exogenous oxytocin administration enhances the placebo effect of classical conditioning and verbal suggestions as measured by subjective pain intensity to a previously validated heat pain conditioning…
Testosterone Therapy in (a)symptomatic, testosterone deficient men after Radical Prostatectomy improves functional and oncological outcome compared to testosterone deficient men who do not receive TRT.
Therapy of psychogenic jerks currently focuses on frequently co-occurring psychiatric disease, but results are poor. In this project, we will study the effect of BoNT on movement disorders of psychogenic origin in a mono centred randomised…