10798 resultaten
1. The intervention groups will have more favourable outcomes on the targeted behaviours and BMI, compared to the control group at follow-up; 2. The "motivational and environmental" tailored intervention group will have more favourable…
We postulate that a set target range of 92%-96% will result in a more stable SpO2 and accompanying reduction of time spent with an SpO2 <91% and similar or less time >96% when compared to a target range of 91%-95%.
Increasing medication adherence in rheumatoid arthritis (RA) might reduce disease activity and the need to prescribe more expensive (biological) anti-rheumatic drugs. The usage of drug monitoring devices (like Medication Event Monitoring System (…
There is no difference between treatment with DMSO and prednisolone in reduction of inflammatory signs and symptoms as measured with a validated compound score (ISS) on the severity of CRPS-1.
We aim to determine the effectiveness and cost-effectiveness of multilevel botulinum-toxin type A injections in combination with a 12-week period of intensive functional physiotherapy exercises (BtA+iPT) and compare this with the effectiveness and…
Not correcting thrombocytopenia prior to CVC placement in patients is non-inferior compared to correcting thrombocytopenia.
Is patient-controlled analgesia with remifentanil more efficacious and equally safe as pethidine as analgesic strategy during ultrasound guided transvaginal oocyte retrieval.
Primary outcome measures: 1. Working Memory (WM) training will lead to an increase of WM capacities; 2. Cognitive flexibility (CogF) training will lead to an increase of CogF capacities; 3. The WM training condition, the CogF training condition and…
We hypothesize that penfluridol as compared to oral second generation neuroleptics (olanzapine and risperidone), will show better compliance (primary outcome) and therefore lower healthcare costs.
The study will test the hypothesis that osimertinib treatment result a partial response in 30 % of patients.
Testing trials: 1. We expect to see a main effect of time on number a) of tests completed b) of persons who get tested c) of tests per person 2. We expect to see a main effect of letter condition. Specifically, we expect that the…
To assess the agreement of COqCO with reference CO values in patients under general anaesthesia in whom fluid is administered, as well as to study the influence of fluid administration on the ability of RPVI to reflect preload dependency.
Comparison between surgical vs non surgical treatment of an atraumatic cuff rupture.
For each of the two treatment arms separately: 1. Null hypotheses (H0): Failure free duration (FFD) at 9 months post allo-SCT = 50%; 2. Alternative hypotheses (H1): FFD at 9 months post allo-SCT = 70%.
PHASE 2: 1. Evaluate medical specialists' perceptions of the concept of care management (in medical education); 2. Based on our findings from the phase 1 study, develop an educational intervention to promote and improve the implementation of…
Patients who develop single-sided deafness (SSD) become aware of the importance of hearing with two ears in everyday listening environments. Current clinical practice for patients with SSD consists of optimizing hearing using a Bone Conduction…
We hypothesize that both cognitive rehabilitation therapy (CRT) and mindfulness-based cognitive therapy (MBCT) positively affect the primary outcome measure subjective cognitive function compared to enhanced treatment as usual (ETAU). Secondarily,…
Outcomes after ABO-incompatible kidney transplantation are favorable compared to ABO-compatible deceased donor transplantation. Due to the desensitization procedure outcomes after ABO-incompatible kidney transplantation will differ from ABO-…
We hypothesize that a dual task (eye movements) during suicidal imagery retrieval will reduce the frequency of such imagery.