318 resultaten
The software of the PlustoptiX devices is developed for pupils up to 7.8 to 8mm in size. In the study “a double blind randomized study on the efficacy of cyclopentolate 1% and tropicamide 1% in children (MEC nr NL32954.098 /1010-077; NTR 2476),…
Parents will improve their communication- and education skills about alcohol-, tobacco-, and cannabis use.
Our hypothesis is that laparoscopic incisional hernia repair comes with a significant shorter hospital stay compared to open incisional hernia repair.
The purpose of our study is to compare the clinical effectiveness and cost-effectiveness of two treatment strategies of intermittent claudication (IC) due to an iliac artery obstruction: to start with supervised exercise therapy (SET) and deferred…
The first two exons of TRPV1 are deleted in the most common mutation found in cystinosis patients: A large 57 kb deletion. We aim to study TRPV1 expression in cystinosis patients both homozygous and heterozygous for this deletion.
Is hydrocortisone safe and effective in reducing the incidence of the combined outcome death or BPD at 36 weeks PMA in chronically ventilated preterm infants, as compared to placebo.
Our hypothesis is that there is no difference in outcome between patients having their incompetent GSV treated with ClariVein therapy using Polidocanol 2%, 3% liquid or 1% foam.
The fenestrated Anaconda endograft is safe for durable exclusion of juxta and suprarenal AAA.
Prevention and treatment of venous thromboembolism (VTE) with low-molecular-weight heparins (LMWHs) is confirmed to be at least as effective as with unfractionated heparin (UFH). In comparison to UFH, the LMWHs have improved pharmacokinetics, ease…
Not applicable: Phase 1 study --> Safety and Tolerability of Nebulized Amoxicillin-Clavulanic Acid in Patients with COPD.
The hypothesis of this study is that omega 3 fatty acid in an artificial tear ameliorates symptoms and ocular surface signs in patients with dry eye.
The effectiveness of a school-based indicated depression prevention program ('Op Volle Kracht') will be tested in a Dutch sample of adolescent girls with elevated depressive symptoms (aged 12-14 years). It is expected that the adolescent…
So far no data on effective treatment for Q fever Fatigue Syndrome (QFS) are availabe. At present, it is unclear whether effective treatment for QFS is possible. The objective of this study is to assess the efficacy of two treatment strategies for…
We expect that oxytocin treatment alone will reduce trauma-related psychopathology at one-and-a-half month follow-up compared to participants who received placebo. fMRI substudy: we expect that a single oxytocin administration will attenuate neural…
The introduction of a virtual asthma clinic may improve the number of asthma free days in children with asthma while the number of visits to the outpatient clinic is decreased by 50%.
Children who attend day care centres are at increased risk of contracting infectious diseases, notably gastro-intestinal and respiratory infections. These not only cause morbidity in the children but also considerable economic costs because of…
We hypothesize that: 1. Patients with mild-moderate and severe asthma have an increased procoagulant activity as compared to healthy controls; 2. Oral corticosteroids activate coagulation in healthy controls and increase the procoagulant activity in…
The intervention, optimal selfmanagement conditions for applying to saltrestriction, improves treatment of hypertension in patients with chronic kidney disease.
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Symptomatic postpartum urinary retention (PUR) is a common complication with a varying prevalence, from 0.5 – 18%. Women who are diagnosed with symptomatic PUR are unable to void within 6 hours after the delivery or have clinical signs of a bladder…