100 resultaten
Transvaginal implantation of ABS system reduces the risk of infection.
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
The gastric balloons are expected to remain in the stomach for approximately four weeks, after which they burst and are fecally excreted. It is further hypothesised that intragastric balloons can provide a surrogate stomach fill, inducing an…
The RAINBOW study: Rheumatoid Arthritis ImplemeNtation of Biological dose Optimization in real World
We hypothesize that a multifaceted implementation strategy can stimulate the use of tight control and bDMARD dose optimization in clinical practice, measured by decreased bDMARD use and non-inferiority on disease activity at 18 months.
Nebulizing amoxicillin clavulanic acid is more effective for reaching amoxicillin levels in sputum > MIC90 than amoxicillin clavulanic acid given by oral or intravenous administration.
It is assumed that recurrence of appropriate ICD shocks is 30% in the Amiodarone group and 16% in the Ablation group.
Chronic allograft nephropathy is the main cause of long-term renal transplant failure. The pathogenesis involves amongst others calcineurin inhibitors. We performed a multicenter randomized trial to study the effects of withdrawal of ciclosporin (…
we hypothesize that an electronic nose can discriminate the VOC pattern in exhaled breath between patients with colorectal cancer and healthy controls.
rt-PA administration by retinal branch vein way in CRVO patients improves final BCVA.
The aim of the study is to examine the effectiveness of Rock and Water (R&W) and possible moderators and mediators. Effectiveness: - The R&W program will increase students’ socio-emotional adjustment (i.e., psychosocial wellbeing,…
we hypothesize that an electronic nose can discriminate the VOC pattern in exhaled breath between patients with Head and Neck Cancer from healthy controls.
Intermittent androgen deprivation using CPA oral monotherapy improves the overall quality of life while achieving similar control of tumour growth to that attained by continuous CPA treatment.
To determine whether a strategy of invasive treatment (relative to continued medical treatment) of patients with type 2 diabetes mellitus, mild symptoms of stable angina pectoris, and documented myocardial ischemia lead to a decrease in cardiac…
Does lipid accumulation in skeletal muscle and the heart effect mitochondrial function in relation to insulin resistance?
Multi-centre open label clinical trial.
Predominantly sleeping in the non-supine position could improve oxygenation and thereby shorten the disease course in admitted COVID-19 patients.
A family involvement program will reduce the number of unplanned readmissions in adult patients undergoing major abdominal surgery.
The aim of this study is to compare the efficacy of EBRT versus SEMS insertion for palliation of dysphagia symptoms in patients with esophageal cancer
Testing for thrombophilia after a first episode of VTE with subsequent prolongation of anticoagulant treatment in thrombophilic patients is beneficial in terms of clinical outcomes, quality of life, and costs.
Speech understanding with a speech processor fitted using the parametric fitting procedure and the recipient's own fine-tuning is as good as with a conventional fitting. The parametric fitting is more patient friendly and less time-consuming.