18 resultaten
1. It is hypothesized that participation in the Active plus program contributes to an increase in physical activity behaviour among older adults; 2. Additionally receiving physical and social environmental information results in an extra increase…
It is assumed that recurrence of appropriate ICD shocks is 30% in the Amiodarone group and 16% in the Ablation group.
Simvastatin (an HMG-CoA reductase inhibitor) induces apoptosis in vitro and sensitizes the myeloma cell to chemotherapy. This is the first clinical trial to test if in vivo there is the same sensitization in relapse or refractory multiple myeloma.
Does lipid accumulation in skeletal muscle and the heart effect mitochondrial function in relation to insulin resistance?
The primary objective of the study ”STOP PAIN” is to compare the effect on migraine attack frequency of transcatheter device closure of atrial shunting with a non-closure group in migraine patients suffering severe migraine with aura.
Administration of fluoxetine during late brain development (adolescence), but not in adulthood, will result in abnormal outgrowth of the 5-HT system. This long-lasting disturbance of the 5-HT system may be visualized using MRI techniques and can…
The relative risk of developing macular edema in diabetics after cataract surgery is enhanced.
Chronic allograft nephropathy is the main cause of long-term renal transplant failure. The pathogenesis involves amongst others calcineurin inhibitors. We performed a multicenter randomized trial to study the effects of withdrawal of ciclosporin (…
Acute Rockwood type 3 AC-luxations will have a better function after operative treatment with the artroscopic TightRope technique than patients treated conservative.
The formula will be tolerated by at least 90% of the children with cow's milk allergy with a confidence interval of 95%.
That the laparoscopic approach should be preferred over the open procedure in cases of an elective sigmoid resection for symptomatic diverticulitis.
Standard localized ligations are as feasible as doppler-guided ligations of hemorrhoid arteries.
Dietary fibres and vinegar has been suggested to lower the postprandial blood glucose and insulin response and this may be explained by a delayed gastric emptying.
The study will investigate the effect of a synbiotic test product compared to a control product on the composition and metabolic activity of the gut microbiota of C-section delivered infants.
The primary objective of this study is to determine whether treatment with Impella compared with IABP therapy after primary PCI reduces infarct size and results in a higher residual left ventricular ejection fraction in acute anterior wall…
Administration of a lipid emulsion consisting of long-chain triglycerides (LCT-trial) in non-trained individuals, will induce insulin resistance due to increased DAG accumulation and subsequent activation of the PKC pathway in skeletal muscle.…
De belangrijkste onderzoeksvraag voor de huidige studie luidt: -wat is de invloed van het cognitief functioneren op de QoL na een SAB op de lange termijn? De twee secundaire vraagstelling zijn luiden: -is er sprake van een specifiek…
Primair doel• Validatie van de accuratesse van MRI met Vasovist® voor de voorspelling van de klierstatus bij patiënten met een primair rectumcarcinoom gebruikmakend van histopathologisch onderzoek van het resectiepreparaat na chirurgie als Gouden…