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A model based on the combination of clinical prognostic factors and features extracted from tumor contours from CTPET has a high accuracy to predict pathologic complete response after chemoradiotherapy in locally advanced rectal cancer.
1. The concentrations serotonin and dopamine are different between carcinoid tumor patients, patients using SSRI, and healthy controls; 2. The concentration free serotonin in plasma, and the ratio free serotonin/serotonin in platelets is determined…
The combination of body brace interface pressure measurements and quality of life questionnaires will improve brace treatment in patients with idiopathic scoliosis
We hypothesize that earlier diagnosis in bloodstream infections results in earlier initiation or adaptation of the empirically started broad-spectrum antibiotics and may lead to an improved patient outcome, decrease in costs and reduction of…
ETMI improves the detection of early neoplasia in Barrett's esophagus.
Our hypothesis is that VR (intervention) will significantly improve the mean NRS for pain after surgery.
Divergent Low Level Laser Therapy as novel treatment for oral mucositis in pediatric cancer patients
What is the effect of divergent LLLT on the number of days of mucositis > grade 1?
Cast treatment is not inferior to surgical open reduction and internal fixation in terms of patient related outcome measurements.
1. testing the feasibility of the use of an hybrid construction of a CardioMEMS PA sensor and HeartMate III LVAD therapy (with permission of the company Abbott). 2. Hemodynamic guidance improves patient outcome and HF hospitalizations by early…
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We expect to find that tumor volume, as well as dynamic contrast enhanced MRI variables will be prognostic variables of treatment outcome
Augmentation of the contralateral hip in patients with a low energy hip fracture over 50Y willdecrease the change of a new hip fracture on the augemented side.
The expectation is that fear of childbirth and additional pain are important reasons for choosing analgesia, or at least influence the choice. An expected reason for not choosing analgesia is that it could be detrimental for the (unborn) child. It…
With the quantification of circulating tumor DNA treatment response assessment will improve in metastatic prostate cancer patients.
Due to the difference in mineralocorticoid characteristics between prednisolone and dexamethasone, it is hypothesized that dexamethasone will have a greater effect then prednisolone, especially when assessing neurocognitive function and blood…
A self-management program including self-treatment of exacerbations, leads to a reduction in the severity and duration of exacerbation compared to a similar self-management program without these self-treatment guidelines in hospital out-patients…
Vitamin K2 can increase the carboxylation of the Matrix-Gla-Protein.
p53 mutation in colorectal cancer provides an immunological window for immune therapy.
Education on guidelines and on communication with parents will improve antibiotic prescribing quality for children with respiratory infections. Providing this education on-line will be a cost-effective approach.
Cytokine expression in lumbar disc tissues correlate with development of chronic neuropathic pain.