2571 resultaten
Unfavorable exposures during the early postnatal period change programming of growth and metabolic pathways, thereby deranging infant’s body composition and increasing the risk for later obesity and diabetes type 2
25% of AMI in patients >17 and <45 years old have a positive toxtyper screening for recreational drug use
Thin strut cobalt chromium stents are not inferior in preventing restenosis compared to sirolimus-eluting stents in patients with acute myocardial infarction.
Is participatory ergonomics for workers with common mental disorders more (cost-)effective on return-to-work than usual clinical medical care?
Intervention with adequate calcium and vitamin D and physical activities will influence BMD and fracture rate in a positive way during and after treatment for childhood ALL.
To determine the efficacy of quetiapine as an adjunct to patients with OCD, without comorbitity, who are newly diagnosed, medication-naive or free. The following hypotheses will be tested: 1. Addition of quetiapine to a SRI increases the number of…
Patients diagnosed with vasospastic angina (VSA) are at increased risk for cardiovascular events. VSA is characterized by endothelial dysfunction and abnormal vasodilatory reserve. Endothelin (ET)-1 is a potent vasoconstrictor peptide produced by…
The study hypothesis is that that daily oral atamestane (100 mg/day), dehydroepiandrosterone (50 mg/day) alone and the combined regimen improve physical frailty, muscle strength and functional performance compared to placebo.
Probiotic supplementation in young infants (1st 2 years of life) has a therapeutic effect, associated with upregulation of tolerance for cow's milk allergens, as well as combined with local and systemic immunomodulation and improvement of…
It is hypothesised that optimizing visualization of the muscle boundries wil improve quantitative muscle ultrasound, which should increase the correlation between the outcome of quantitative muscle ultrasound and magnetic resonance imaging.
The efficacy of low dose amitriptyline on insomnia is equivalent to first choice treatment CBT-I.
- The effectiveness of an ACT intervention focused on values and willingness to take action is more effective in reducing depressive symptoms two weeks after the intervention, compared to an an ACT intervention focused on acceptance and defusion and…
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
Survival of transfused erythrocytes will depent on donor and unit characteristics
Based on a pilot study from the Amsterdam University Medical Center, we hypothesize that the FET is possibly less accurate to detect EPI in patients with pancreatic cancer and after a pancreatoduodenectomy (PD).
It is hypothesized that the new cement compression device leads to better cement distribution and penetration compared to the current technique (finger packing). It is also hypothesized that there will be less cement leakage and that the duration of…
The main study parameter is the agreement between ribociclib plasma levels of blood collected by venipuncture or DBS.
Individual Placement and Supported will be cost-effective in achieving regular (open, paid) employment. Differences between countries in the effectiveness of IPS can be explained by socio-economic variables like the employment rate and for instance…
We hypothesize that suppression of the gonadal axis will increase bone marrow and visceral fat in biological women and men and subsequent administration of estradiol or testosterone will decrease the amount of bone marrow and visceral fat. We…