22 resultaten
Many employees who are sicklisted do not really know how to handle the situation. Simple and specific education and individually based instructions through a website can possibly solve or reduce this problem. Besides, the website contains a…
The RAINBOW study: Rheumatoid Arthritis ImplemeNtation of Biological dose Optimization in real World
We hypothesize that a multifaceted implementation strategy can stimulate the use of tight control and bDMARD dose optimization in clinical practice, measured by decreased bDMARD use and non-inferiority on disease activity at 18 months.
rt-PA administration by retinal branch vein way in CRVO patients improves final BCVA.
Testing for thrombophilia after a first episode of VTE with subsequent prolongation of anticoagulant treatment in thrombophilic patients is beneficial in terms of clinical outcomes, quality of life, and costs.
In this double-blind randomized controlled trial, we would like to show that a five-day treatment course with 16mg/day oral dexamethason is effective in inducing recovery from an exacerbation of MS.
We hypothesis that antiplatelet therapy adjunctive to rt-PA thrombolysis improves outcome by preventing re-occlusion in terms of three months clinical outcome.
A restrictive fluid regimen is beneficial for postoperative recovey after abdominal surgery, as to hospital stay and postoperative complications.
By inducing a shift of fat out of the visceral compartment - among which the pancreas - into the subcutaneous compartment rosiglitazone results in improved pancreatic beta-cell function in type 2 diabetes patients, as compared to a…
Hypothesis 1: Participants who receive either of two CBM interventions will reduce their gambling more than participants completing the placebo intervention immediately after the re-training (post-intervention assessment) and by the 3-and 6-month…
The main objective of this randomized, placebo-controlled trial is to determine the effects of cinnamon extract on HbA1c and lipid profiles in type 2 diabetic patients.
Percutaneous, ORIF and conservative treated of displaced intra-articular calcaneal fractures have a similar outcome as measured with the AOFAS (American Orthopaedic Foot and Ankle Society) score.
As EGFR plays a role in pathogenesis of both pulmonary arterial hypertension and systemic sclerosis, EGFR inhibition will lead to beneficial effects in disease course.
The aim of this study is to assess the predictive value of the HowRwe questionnaire in relation to the EUROPEP questionnaire by analyzing scores acquired in Dutch GP practices. We expect that high HowRwe scores are associated with an positive…
Insulin detemir, when injected once daily at an individually appropriate time (either before breakfast or at bedtime), provides superior glycaemic control to insulin glargine injected indiscriminately at bedtime in patients that had clearly…
It is expected that STIP shows superior efficacy in terms of faster improvement in the first 12 months of the trial and a higher recovery rate at 24 months of follow-up. In addition, it is expected that the higher direct medical costs of STIP are…
A cesarean section performed without a clear indication results in additional morbidity and costs without improvement of outcome. The group of women delivering their first baby in cephalic presentation at term is the largest contributor to the…
Het doel van dit onderzoek is het evalueren van de veiligheid en effectiviteit van een gefaseerde epicardiale en endocardiale ablatieprocedure bij patiënten met persisterend of langdurig persisterend boezemfibrilleren door middel van een…
De studie bestaat uit 2 delen. Deel 1: Evaluatie van het seksueel functioneren van MRK(H) vrouwen, het seksueel zelfbeeld, psychologisch en relationeel functioneren van deze vrouwen en het seksueel functioneren van hun partners en vergelijken met…
Het doel van deze studie is het onderzoeken of de verschillen in DNA methylatie, die gezien zijn bij zij die blootgesteld zijn tijdens de zwangerschap aan de Nederlandse Hongerwinter,door worden gegeven aan een volgende generatie.