309 results
With this study we want to measure the two parameters who determine the hemodynamic status of the brain tissue. The first parameter we want to determine is the Cerebrovascular Reactivity (CVR), which is a measure for the degree in which blood…
To set up a repository of genetic material from a large group of well phenotyped people with epilepsy patients to allow the case control association studies, and families for linkage studies, to analyze and detect genetic risk factors for epilepsy.
Primary objective: The general aim of this study is to elucidate the role of the glycocalyx in the pathogenesis of DCI in SAH and to study the effects of magnesium on glycocalyx volume.Main objectives of this proposal are:- To assess whether the…
Is the radiological, histological and biomechanical condition of bone altered after long term bisphosphonate treatment in bone that is subjected to either compressive of distractive forces.
1) Prevalence of celiac disease in a Dutch cohort of adult type 1 diabetes patients. 2) Investigation of the long term complications of type 1 diabetes patients with concomitant celiac disease
The results are used to develop a computer model that can predict speech intelligibility for hearing impaired people, even after signal processing. A model like that can be used to choose the most optimal hearing aid settings in the future.…
Aim is to compare the development of children placed in foster care without receiving treatment (regular foster care) and children placed in foster care and receiving treatment (therapeutic foster care).Research outcomes determine the effect of…
Research of lung function and exercise capacity in late preterms (32-36 weeks gestation) in comparison with term born controls of 8 years
The objectives of this study is to determine the recovery and survival of platelet concentrates; in the first phase, a comparison will be made for platelet concentrates in plasma stored for 2-3 days versus those stored for 6-7 days; in the second…
Identify DNA methylation markers suitable for sensitive and specific plasma-based detection of advanced colorectal adenomas.
The search for correlations between components of the diet and the group has experienced a hip fracture. These findings are compared with healthy elderly. The results can contribute to nutrition -focused interventions in future studies .
To measure the quality of peripheral visual field in healthy volunteers and the effect of different corrective lenses on the peripheral visual field.
The objective of this proposal is to investigate if duloxetine is effective as a third choice pain medication for treating chronic pain in OA compared to usual care. Furthermore, we will assess the cost-effectiveness of duloxetine treatment and if…
In this study, the following questions will be answered:1. Does larval therapy accelerate wound healing?2. Do single larval secretions accelerate wound healing?3. Is the bacterial load in the wound reduced during larval therapy or is the microbiome…
The objective of this study is to evaluate safety and blood pressure response after renal denervation in patients with uncontrolled hypertension on three standard antihypertensive medications compared to a sham-controlled population. These data, in…
Primary Objectives:The primary objectives are to evaluate in infants who are hospitalized with RSV infection:- the pharmacokinetics of JNJ-53718678 after multiple oral doses;- the safety and tolerability of JNJ-53718678 when administered for 7 days.…
To assess arterial wall inflammation, measured with 18F-FDG PET/CT scan, in patients with intermediate and severe FH phenotype, as well as the change in arterial wall inflammation following PCSK9 inhibition.
The aim of the proposed study is to investigate the presence of dopaminergic abnormalities in relation to apathy in persons with a high risk for psychosis. Second, we intend to explore the relation between the dopamine system and apathy in general,…
Primary Objective: To determine if spinal and cortical balance control mechanisms mediate the age-associated decline in balance skills. Secondary Objective: To determine the reliability of TMS and H-reflex measures in the soleus muscle in different…
The objective is to investigate the correlation between bacterial/viral gut infections and acute appendicitis in children.