66 results
The first (primary) objective (study 1) is to examine 1a) risk factors for volume loss in the entorhinal cortex and compare these with risk factors for volume loss in the rest of the hippocampus at 1.5T MRI over 7 years of follow-up; and to examine…
To assess the impact of OH on cerebral perfusion and function in severe OH in AF (n=10) and healthy controls (n=10).
Primary objective: To determine whether the short-term neurological outcome of surviving children diagnosed with prenatally diagnosed ventriculomegaly is associated with the extent of VM before birth.Second objective: To determine whether the…
To evaluate the efficacy of various masking strategies in cochlear implants as a treatment for tinnitus in patients with profound hearing loss.
to measure neural activity of the central nervous system in tinnitus related brain areas in cochlear implant recipients with chronic tinnitus and to determine the relation between this neural activity and the subjective tinnitus experience of…
Does anesthesia itself or transition of anesthesia to an awake state and vice versa lead to changes in the lactate/pyruvate ratio, glucose, glycerol and glutamate concentration as measured in the brain interstitial fluid?Are the metabolic…
To determine the feasibility and the estimation of the effect for the primary study parameter of a cognitive rehabilitation treatment for deficits in social cognition after traumatic brain injury.
Translation follows at a later stage.
The aim of the present study is to investigate cerebral vasoreactivity in response to lower body negative pressure in young and elderly healthy men, as a measure of cerebral autoregulatory responsiveness.
To evaluate whether GH substitution in patients with an isolated GHD after TBI could reverse the severity of symptoms which characterize GHD.
The eventual aim of the study is to determine the effects of Botulinum toxin injections in the bladder on overactive bladder. The objective of this initial study is to determine what brainstructures are activated in respond to increasing volumes of…
Primary Objective: In this study, we will investigate the feasibility of a newly developed methodology for diagnosing the visuoperceptual hemifield abilities of young children with early damage to the visual system. Secondary Objective(s): Secondary…
To study the acute effect of HD on global and regional CBF.
Primary Objective: • To demonstrate that changes in blood pressure and cerebral perfusion (induced with paced breathing and the Cold-pressor test) can be assessed in the MRI using the combination of NIBP and rapid ASL measurements. Secondary…
To assess how measures of microvascular function on 7T MRI in individuals from the Rotterdam Study without a history of clinical stroke or dementia relate to:- Exposure to vascular risk factors - Severity of presymptomatic SVD lesions- Cognitive…
The general objective of this study is to gain more understanding of motor and cognitive impairment and the way these two are linked after stroke. There are two more specific objectives: exploring (1) the link between motor and cognitive impairment…
Primary Objective: To test the feasibility of online neuropsychological assessments using the Amsterdam Cognition Scan (ACS) compared to classical neuropsychological assessments in patients with cancers with CNS involvement.
Primary ObjectiveOur primary objective is to investigate the effect of SVD-progression on the long-term clinical outcome. Secondary Objectives- To identify causes and risk factors related to an unfavourable clinical outcome over time- To identify…
This study has been transitioned to CTIS with ID 2024-517636-22-00 check the CTIS register for the current data. The main objective of the present study is to investigate the association between in vivo regional synaptic loss ([18F]SynVesT-1 PET),…
The objective of this study is to validate the VBMEG algorithm by comparing hd-EEG with fMRI activity. If validated, it will be validated that the accuracy of the VBMEG algorithm is improved when fMRI is incorporated to the source reconstruction,…