143 results
The specific aim of the project is to determine the efficacy of Spherical Nucleic Acids (SNAs) on psoriasis skin biopsy gene expression in vitro.
We aim to investigate whether reinstatement of cortical representations are necessary for successful memory retrieval.
Feasibility of knee motion reproduction method for application in a hinged knee distraction device to apply reliable comfortable hinged knee joint distraction to be tested in future clinical studies.
1) To perform gene mutation analysis in family members of patients carrying a proven mutation in the candidate gene.2) To determine the clinical, biochemical and radiological characteristics of carriers of a mutation in the candidate gene.3) To…
In this study we would like to investigate the effects of denervation on the cortical representation of finger articulations. We will assess the decodability of six different hand gestures from the American Manual Alphabet in people with an…
We aim to measure the vitamin D status (25(OH)D) and prevalence of vitamin D deficiency in Western and non-Western infants and toddlers aged six months to four years in the Netherlands. We will assess the cross sectional association between vitamin…
Determination of volume and surface area of intramuscular oil depots during body clearance using MRI
The aim of this research is to determine the surface area of an oil depot during oil clearance. This is relevant for the release rate and therefore for the absorbed amount of active substance in blood. The volume is important for the interstitial…
1.Social CognitiveA.Do schizophrenia patients, compared to unaffected controls, show impaired social cognition (perceiving, understanding, intentions and emotions of others), especially when it comes to self-other distinction processes (…
To assess the effects of vaginal prolapse surgery on microcirculatory parameters measured in the vaginal wall with the use of incident dark field (IDF) imaging (Cytocam).
1. To determine the optimal acquisition technique for USPIO enhanced MRI (without contrast injection), DCE (without contrast injection) and DWI and T2* MRI of esophageal cancer in terms of signal-to-noise ratio, time resolution and spatial…
The aim of the study is to strengthen the basis for a new application of pupillometry (i.e., the measurement of pupil dilation) within the field of Audiology. An innovative method to quantify listening effort (pupillometry) will be further developed…
The main objectie of the study is to map the developmental trajectory of processing perceptual and social information in infants using fNIRS. In addition, with the measurement in 5 month-old children we aim to replicate previous research. The…
We hypothesize that perioperative ketamine will reduce cognitive decline in postoperative patients, in line with its analgesic and anti-inflammatory properties. There are no previous data available on the effect of ketamine on postoperative…
The primary objective is to study attachment in young children through skin-warming.
The primary aim of this project is to examine the impact of heart failure on functional sympatholysis.
to compare in vivo total kidney 123I-MIBG uptake (by counts per pixel) by 123I-MIBG scintigraphy to direct ex vivo 123I-MIBG uptake of the flushed kidney as directly assessed with phosphor imaging.
Incidence of type 2 diabetes mellitus and cardiovascular disease in familial combined hyperlipidemia
To determine: 1) the incidence of type 2 diabetes mellitus in FCHL patients, normolipidemic relatives and their spouses2) the incidence of cardiovascular disease in FCHL patients, normolipidemic relatives and their spouses3) the prevalence of CESD…
Primary Objective: The primary objective of the current study is to measure the neural activation involved in transitioning from freeze to fight, in healthy subjects.Secondary Objective(s): To measure connectivity patterns related to freeze and…
The objective of this study is to assess whether oral exposure to beer and non-alcoholic beer elicits similar reward responses in the brain in a setting where only beer is expected. This knowledge will give fundamental insight in whether alcohol is…
This study addresses the following three questions:1. How do fear memories change over time?2. How is the context of fear coded in the brain?3. How can the process of excessive strengthening of fear memory be disrupted