81 results
Primary Objective- To evaluate the long term safety and tolerability of treatment with CP-690,550 (10 mg BID or variable dose 5 and 10 mg BID) in adult subjects with moderate to severe chronic plaque psoriasis who are candidates for systemic therapy…
The specific aim of the project is to determine the efficacy of Spherical Nucleic Acids (SNAs) on psoriasis skin biopsy gene expression in vitro.
The aim of the project is to study the effect of "CD11781/I, CD10394/101A and CD11406/B" on typical skin features of psoriasis. Thisinformation can establish the most effective compound, right formulation and dose for further clinical…
The specific aim of the project is to determine the efficacy of Spherical Nucleic Acids (SNAs), delivered in a gel, on psoriasis skin biopsy gene expression in vitro.
The main objective of the study is to see if the test compounds can prevent the development of a psoriatic lesion induced in non-lesional skin from psoriasis patients which has been transplanted onto immune-deficient mice.
The aim of the project is to study the effect of KY1005-2D10 on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical research.
The primary study objective is to examine functionality and usability of a newly developed eHealth and serious gaming intervention, to ensure that the intervention is user-friendly and fits the needs of potential users. Based on these functionality…
In this study the efficacy of a novel monoclonal antibody on the development of psoriasis in the humanized mouse model will be investigated.This experimental compound will be compared with 2 registered drugs, i.e. Humira en Stelara.
To see if the new drug can prevent development of psoriatic changes in the transplant model of psoriasis
To see if the new drug can prevent development of psoriatic changes in the transplant model of psoriasis
Research questions:What is the current prevalence of latex allergy among operating room employees from Erasmus Medical Centre, Rotterdam? Is the sensitisation prevalence significantly lower compared to the prevalence before introducing non powdered…
Test efficacy of compound B in humanized mouse model of psoriasis.
In this study the dose reponse of compound MT204 on the development of psoriasis in the humanized mouse model is investigated. The efficacy of MT204 is compared to two registered drugs, namely Ustekinumab and Daclizumab.
Test efficacy of compounds D+E in humanized mouse model of psoriasis.
Overall aim: To study the influence of M.leprae antigens on differentiation and maturation of DCs and to identify M.leprae antigens, receptors on antigen presenting cells and signaling pathways which play a role in leprosy pathology. Main objective…
Is topical application of compound Z effective in reducing the development of psoriasis, induced in this humanized mouse model?
The primary goal is investigating the number of women that have lymphedema five years after the treatment for breast cancer. In the describing part of this study, the focus will be on the correlation between lymphedema and 1) surgical treatment, 2)…
This research aims to conduct blistering and reduce freguent dressing changes in patients undergoing total hip replacement or total knee replacement have undergone in the use of Aquacel Surgical dressing.This compares with the usual method of wound…
Are Alphabodies against IL23 effecive in the transplant model of psoriasis
1) To determine the prevalence and the sensitivity for various antibiotics of Staphylococcus aureus in the nose (carrier) of patients visiting the outpatient department of Dermatology.2) To determine the prevalence and the sensitivity for various…