184 results
Several observational studies have shown that Citrus/Cydonia comp. might be an effective treatment option for patients suffering from seasonal allergic rhinitis. In these studies Citrus/Cydonia comp. was either administered subcutaneously or given…
The primary objective of this study is to evaluate the effects of two types of AR treatment & placebo in counteracting AR*s effects on Cognition and Driving. Therefore, the effects of nasal provocation in AR patients on cognitive functions…
Primary endpoint:Measuring lymphocyte response in patients with suspected pulmonary bird fanciers lung by ELISPOT technique.
The aim of this study is to develop and validate the basophil activation test by flow cytometry in our hospital as an extra diagnostic procedure for patients, who can not be diagnosed with existing tests or who have the risk of developing…
To compare the efficacy and safety of methotrexate versus azathioprine treatment in adult patients with chronic severe AD.
The main aim of this study is to assess the prevalence of allergic and non-allergic health problems in veterinary students in different phases of the veterinary education. On later stage, genetic predisposition for allergies will be studied. In the…
The main aim of this follow-up study is to assess the incidence of respiratory disorders, like allergy, asthma and asthma like-syndrome, in association with the interaction of environmental and genetic risk factors in veterinary students. In order…
The aim of the study is to determine the biological activity of specific IgE antibodies and allergens.
To compare the MC with the UK working party diagnostic criteria (UKC) and clinical diagnosis and to refine the MC into a more convenient and reliable set of criteria.
Investigate the role of CD8+ T cells in AD by:a. Isolation of T cells from the skin and determination of the percentage and phenotype of CD8+ T cells in both acute and chronic AD, using the APT as an in vivo induction model. Comparison with…
We hypothesize that expiratory VOC-analysis by electronic nose is capable of:1. Discriminating between asymptomatic infants and infants with respiratory wheeze.2. Discriminating between parent-reported and doctors-confirmed wheezy infants.The aim of…
We hypothesize that local AMPs expression in the airways of patients with asthma is decreased as a result of allergic inflammation. Furthermore, we hypothesize that local AMP expression can partly be restored by vitamin D substitution therapy. We…
Although it is known that Tregs have an important role in the induction of tolerance in allergen immunotherapy, more research into the different populations is necessary. The recent developments in FOXP3-stainings together with intracellular…
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Identification of low allergenic apple cultivars and breeding germplasmIdentification of chains in which low allergenicity is preserved and of the critical steps in the chain for preserving low allergenicity.
In this pilot study we intend to measure Tregs in umbilical cord blood, in normal as well as in pregnancies complicated by preeclampsia, and will define their use as a predictor of the risk for developing allergic diseases in the child.
Primary Objective: What is the frequency of positive patch test reactions to the 26 declarable fragrance allergens in fragrance mix I and/or II positive participants?Secondary Objectives: Do Weleda cosmetic products containing essential oils,…
The aim of this study is to identify cow's milk protein T cell specific epitopes in children with cow's milk allergy. The results of this study will be implemented in a controlled, prospective follow-up study, *Cow*s milk allergy: a clue…
Objective: How do T cells in cord blood respond to heat shock proteins, allergens and anti-CD3 Are stimulus specific Tregs induced during these responses and can these responses be suppressed by naturally occurring cord blood Tregs in vitro.
To assess 1. the burden of allergic disease across Europe*s aging population2. the association of severe asthma with potential risk factors and their impact on lung function decline over time3. the association of asthma severity with sex hormone…