224 results
Investigation of sensitivity and specificity of symptom validity tests for clinical use in neuropsychological assessment by patients with ADHD. Calculating measures that are indicative of suboptimal effort in regular neuropsychological tests for…
The overall aim of the study is to enrich the database of the Dutch IMAGE samples with (1) structural magnetic resonance imaging (sMRI) and functional MRI (fMRI) data; (2) follow-up data of clinical status (ADHD symptoms and relevant comorbidities)…
The purpose of this trial is to research how the new medication SCH 900062 after single and multiple dosing is absorbed, broken-down and excreted by the body when in the fasting state and after eating a high fat meal. This trial is necessary for the…
Primary researchquestion:1. What are the differences in eye-hand coordination in patients with left or right hemisphere damage compared to healthy age-matched controls?Secondary research questions:2. What is the difference in eye-hand coordination…
The primary objectives of the iSPOT-A trial are to use Brain Resource's standardized 'Integrative Neuroscience' test batteries to 1) Identify objective markers of ADHD compared with healthy controls, using cognitive, brain and genetic…
The proposed research has several objectives:1) By implementing a cognitive testbattery in a large population of forensic psychiatric patients, a prison population and healthy controls, we will be able to further develop and adjust the battery…
Decreasing AB and subsequent craving through attention training in alcohol dependent patients. Further, we will investigate whether the risk for relapse diminishes after the training. Long term goal is to investigate the effect of attention training…
In our own recent studies we found indications of the existence of particular executive functioning deficits as well as memory impairments following different regimens of cytotoxic agents. Together with the indication from our animal study of a…
1) To investigate the relative contribution of different neurocognitive dysfunctions toADHD.2) To identify potential baseline EEG/MRI markers of different neurocognitive functions in ADHD children and healthy controls.
The objectives of this study are to establish whether methylphenidate PD effects can be measured using neurocognitive tasks, to describe the drug concentrations of methylphenidate in saliva, to describe the PK/PD relationship using the obtained…
Primary Objective: Using functional neuroimaging to assess differences in brain activation during WM at low and high load with emotional versus neutral distracters in participants with PTSD and in healthy participants with and without stress.…
The research question targets the validation and examination of norm scores of the ToM test-R test in the mental disorders PDD, ADHD, and social phobia in children of different ages. It will be investigated:(1) Whether or not differences in *theory…
The objective of the pilot study is to investigate whether a neurofeedbacktraining is a feasible intervention for youngsters with AD(H)D and severe behavioral problems. Besides the feasibility of the neurofeedbacktraining the clinical relevance of…
The primary aim of this study is to identify the psychosocial determinants of stress (vulnerability) and cognitive complaints in breast cancer patients treated with adjuvant radiotherapy. The stress model of Taylor and Aspinwall will be used.
Primary:The primary objective of this study is to evaluate the efficacy of LDX administered as a daily morning dose (30, 50, and 70mg/day) compared to placebo over the course of 7 weeks. This study will enrol children and adolescents (6-17 years of…
To investigate sleeping disorders in adults with ADHD, especially sleep onset disorders related to the circadian rhythm. Furthermore, the etiology (DNA) as well as possible additional chronobiological and general health variables will be addressed.
The aim of the present study is get more insight into the effects of alcohol on acute changes in brain communication en behavioral inhibition. It is hypothesized that alcohol will result cause impairments in the ability to inhibit behavioral…
By restricting the inclusion on the fMRI studies to participants with deficits on a specific domain we hope to examine the unique neural mechanisms contributing to specific impairments. This will allow us to address the question whether…
In this project, we will examine whether the simultaneous recording of ERPs and fMRI during the adapted grating task results in data of sufficient quality. More specifically, we would like to know 1) whether the components normally observed in the…
1.To describe whether vascular lesions are more frequent in elderly heart failure patients compared to elderly patients with cardiovascular disease but no heart failure.2.To describe the association between these vascular lesions and executive…