28 results
Primary objective:To assess the efficacy of BMN 045 after 48 weeks treatment in ambulant subjects with Duchenne muscular dystrophy.Secondary objectives:To assess the safety and tolerability of BMN 045 after 48 weeks of treatment in all study…
Primary objective of this study is to assess the reliability, validity, and diagnostic value of the neuromechanical parameters of joint impedance estimated by nonlinear SIPE technology in patients with a spastic paresis.
To determine whether the intake of minced beef is equally effective as ingestion of a bovine milk protein beverage in stimulating post resistance exercise muscle protein synthesis rates in young men.
The aim of this pilot study is to test the feasibility of a screeningset, to be used in a future cross-sectional study on the prevalence, characteristices and health and economic outcomes of sarcopenia in community-dwelling older people.
Primary ObjectiveDifference in incidence of an avulsion injury and morphological changes of the levator ani muscle after a first normal vaginal delivery between participants with and without a mediolateral episiotomy.Secondary ObjectiveChanges in…
Obtain information regarding the movement abilities and muscle strength in persons with several neuromuscular diseases, which can be used to develop a motion controlles arm suport for daily use and training of arm function.
The purpose of this study is to examine the feasibility of both the CPET and the 6MWT as outcome measures for exercise capacity in children with DMD and BMD. This study will focus on ambulatory children with DMD and BMD. These patients frequently…
In this study we want to investigate if the muscle-relaxation time (muscle-RT), calculated from force profiles obtained with two different experimental methods (1) voluntary handgrip- and (2) peripheral nerve stimulation myometry, is a reliable and…
To investigate the effects of 5 days of one legged knee immobilization with or without daily NMES on quadriceps CSA, lean mass and muscle fiber characteristics.
To determine whether 3D arm training with arm-support is effective in delaying the loss of arm functions in daily activities from an early age onwards in boys with DMD.
This study aimes to investigate wheter or not a fasciotomy of the deep posterior compartment of the lower leg leads to a lowering of the intracompartimental pressure, an objective parameter. . This study will also investigate wheter or not a…
Is it possible to make a discrimination in muscle activity between the right and left puborectalis muscle by using concentric needle electrodes in an electromyography investigation of the pelvic floor muscles?When a asymmetry is found, what can be…
Primary Objectives:1: Gain insight in the way arm function changes during the natural course of DMD through 3D movement analysis, surface electromyography and ambulant activity monitoring.2: Investigate if a newly developed exoskeleton is able to…
To validate and determine the accuracy of an inverse model for determining motor unit properties based on high-density surface EMG measurements from biceps brachii and tibialis anterior muscles.
To investigate whether patients with VLCADD have a different energy metabolism compared to healthy controls.
To determine the effect of levosimendan on diaphragm function in mechanically ventilated patients.
The aim of this study is to investigate the effect of a single bout of NMES on muscle protein synthesis rates in healthy elderly males.
The objective of the study is to investigate the effectiveness of a combined intervention on the disabilities, self-efficacy and long-term employability of workers with complaints of the arm, neck and / or shoulder. Through a self-management program…
Primary Objective: Is there reduction in pain using an abduction brace in patients undergoing arthroscopic cuff repair? Secondary Objectives: - Are there differences in function and recovery of the cuff, determined using questionnaires and echo?- Is…
T\o evaluate the pharmacokinetics, safety and tolerability of the research medication