319 results
To get insight in the current care for mood disturbances after stroke, by identifying best practices and needs as experienced by patients and healthcare professionals.
Primary Objectives* To assess the safety and tolerability of Foxy-5 in subjects with colon cancer.* To assess circulating tumour DNA (ctDNA) in plasma as a surrogate parameter for disease recurrences in subjects with Wnt-5a low colon cancer treated…
The aim of the present study is to causally detect whether disrupting processing in the numerosity map with TMS alters numerosity perception and/or object size perception.
Aim 1: Confirm the hypothesis that the IgG4 qPCR test score correlates with disease activity in vasculitis as observed in the pilot study. Aim 2: Study IgG4-expressing B-cells from blood of vasculitis patients to understand their role in the…
To explore the multimodal correlates of cognitive functioning through the framework of *multilayer connectomes*, in which EEG/MEG/rsfMRI/dMRI will each be represented as layers of the brain network, and MRS will be used to further investigate the…
The objective of this study is to determine the difference in maximal dorsoflexion angle of the ankle when performing the weight bearing dorsoflexion lunge test between patients with a chronic midportion Achilles tendinopathy and healthy controls.
To gain insight into the biological pathways that are influenced by the CEEx30/31 mutations.
Primary Objective: Evaluate the relationship between the amount of pollen collected in the environment of the hay fever sufferers using a handheld sniffer and the symptoms of these subjects.
Primary Objective: To investigate diastolic LV dysfunction before and after 6 months anti-inflammatory treatment with TNF blockers in patients with RA, assessed by exercise-stress echocardiography.Secondary Objective: To investigate whether systolic…
The main aim of this study is to investigate if patients that received an ankle arthrodesis, have arthritis in the adjacent joints (subtalar joint and talonavicular joint). Furthermore, we would like to study (1) the amount of increase of arthritis…
This study aims to determine the digestibility of AAs in two protein sources in men and women with normally functioning ileostomies.
The study objective is to assess whether negative and positive outcome expectations, induced by verbal suggestions under both open- and closed-label conditions, can influence itch during a short-term validated histamine test. Additionally, we…
The properties of CBD, namely potential effects on variables pertaining to fear extinction and potentially on fear retention/reinstatement while having non of the problematic side-effects found in *9-THC, make CBD plausibly preferential over *9-THC…
In this project we will establish primary keratinocyte cell lines of patient skin biopsies from selected skin diseases, to generate 3D skin constructs. In addition, patient DNA will be genotyped for genetic risk factors (psoriasis and AD) or…
To assess the effect of a fixed dose of licorice with a specified amount of glycyrrhizic acid on blood pressure, potassium and sodium levels and cortisol/cortisone balance in normotensive subjects. In order to explore individual genetic influences,…
We select patients that have a diagnosed anxiety disorder and are already enrolled to start an intensive exposure therapy program at Pro Persona/Overwaal. In an fMRI session their individual underlying neural mechanism (biomarker) associated with…
Objectives: The main objective is to study renal tissue in relation to renal function before and after nephrectomy with a specific focus on microvascular structure and function. A second objective is to study renal microvascular alterations in…
Assessment of emotion recognition in patients who suffered an ischemic cerebellar stroke in the past 3 years.
The current pilot study aims to assess whether it is possible to create a genital reaction by means of excitation transfer and what are the optimal parameters to induce this effect.
The aim of the project is to study the effect of JW 1-3 test compounds on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical research.