21 results
A fundamental question in the current research proposal concerns how changes in cognitive and social-emotional behavior are related to functional and anatomical brain development. The current proposal has the objective to (a) understand the neural…
We aim to document the brain anatomy and functioning and development of children and adolescents of different ages who suffer from Prader-Willi syndrome in order to gain insight into the possible relation between the observed behavior and the brain…
The primary objective of the REBEL study is to collect data needed to design control policies to diminish the spread of ESBL-producing Gram negative bacteria in the Dutch population.
The first aim of this study is to extend clinical knowledge on NPC. This has several reasons:1) The heterogeneous clinical presentation of NPC makes extensive clinical knowledge amongst physicians a prerequisite in preventing diagnostic delay.…
Primary Objective: The here described study aims to strengthen the recently obtained results regarding increased expression of PK antigen in patients with PK-deficiency. This will be achieved by increasing the number of investigated patients and…
The objective of this study is to learn from young people with a chronic illness (diabetes or progressive muscular disease) who have found a balance between taking good care of their illness and having a good life. This study examines how these…
1. To include the patients* point of view in the characterization and description of the mucopolysaccharidoses; and to compare between the different types of mucopolysaccharidoses.2. To assess *health damage* at the moment of diagnosis, in order to…
Objectives are: A. to assess the incidence of ABI in children and youth (up to 25 years of age). B. to describe the consequences of ABI, restrictions in participation and health care needs 2 years post-onset, as well as associated factors.
To determine the replication history of DS-B-lymphocytes by KRECs in relation to somatic hypermutation.
The main objective of the study is to investigate the course of the mental health and quality of life of maltreated children after they have been reported to a Child Protection Agency (CPA). Secondary objectives are: (1) to examine how theoretically…
1. To determine the reproducibility and sensitivity of the EC of walking test in boys with DMD, in comparison with the reproducibility and sensitivity of the 6MWT. 2. To evaluate the one-year course of limitations in ambulation among boys with DMD,…
Research GoalsUsing cross-sectional data we will test whether control and affective brain regions follow different developmental time courses. The first study will focus on the development of inhibitory control (stimulus-driven and intentional),…
The primary objective of this sutdy is to further investigate attention and MSI in adolescents with ASD. To do so, the following tasks will be administered. Task 1 Clock task: multisensory integration and the effect of sound on the velocity of the…
We aim to answer the following research questions:What is the prevalence of child maltreatment in the Netherlands?Which types of maltreatment are prevalent and how are they interrelated?What are characteristics of the victims of child maltreatment?…
To study the effects of changing consultations by starting with the patients agenda on the enablement of children with asthma and their parents to bring forward their questions, worries, problems and beliefs.
Social and emotional functioning of hearing impaired children, in the agegroup between 9 and 15 years old.
Evaluate the effect of topical steroids on salivary cortisol levels, and assess the correlation between salivary cortisol levels, symptoms of asthma, and lungfunction in children with asthma and/or rhinitis
The global aim of the proposal is to expand our knowledge on the functioning of the fronto-striatal system and the relation to behavioral rigidity, and how these are affected by dopaminergic modulation. The specific aim is to study the effects of…
The main objective of this study is to investigate whether the immature neural circuitry of the adolescent brain is an advantage when it comes to creative cognition.
The objective of the studie is to develop a reliable and discriminative measurment protocol to determine the upper extremity function in boys with DMD. This measurement protocol will be based on 3D movement analysis and surface EMG measurements.