197 results
The effects of intravenous TRH administration on brown adipose tissue activity in healthy, lean men.
To investigate whether BAT tissue can be activated by intravenous administration of TRH. Secondary objectives are to determine whether intravenous TRH increases the degree of cardiovascular sympathetic stimulation and the response of skin…
The specific aim of the project is to determine the efficacy of Spherical Nucleic Acids (SNAs) on psoriasis skin biopsy gene expression in vitro.
We aim to investigate whether reinstatement of cortical representations are necessary for successful memory retrieval.
Feasibility of knee motion reproduction method for application in a hinged knee distraction device to apply reliable comfortable hinged knee joint distraction to be tested in future clinical studies.
1) To perform gene mutation analysis in family members of patients carrying a proven mutation in the candidate gene.2) To determine the clinical, biochemical and radiological characteristics of carriers of a mutation in the candidate gene.3) To…
In this study we would like to investigate the effects of denervation on the cortical representation of finger articulations. We will assess the decodability of six different hand gestures from the American Manual Alphabet in people with an…
We aim to measure the vitamin D status (25(OH)D) and prevalence of vitamin D deficiency in Western and non-Western infants and toddlers aged six months to four years in the Netherlands. We will assess the cross sectional association between vitamin…
Determination of volume and surface area of intramuscular oil depots during body clearance using MRI
The aim of this research is to determine the surface area of an oil depot during oil clearance. This is relevant for the release rate and therefore for the absorbed amount of active substance in blood. The volume is important for the interstitial…
1.Social CognitiveA.Do schizophrenia patients, compared to unaffected controls, show impaired social cognition (perceiving, understanding, intentions and emotions of others), especially when it comes to self-other distinction processes (…
To assess the effects of vaginal prolapse surgery on microcirculatory parameters measured in the vaginal wall with the use of incident dark field (IDF) imaging (Cytocam).
1. To determine the optimal acquisition technique for USPIO enhanced MRI (without contrast injection), DCE (without contrast injection) and DWI and T2* MRI of esophageal cancer in terms of signal-to-noise ratio, time resolution and spatial…
The aim of the study is to strengthen the basis for a new application of pupillometry (i.e., the measurement of pupil dilation) within the field of Audiology. An innovative method to quantify listening effort (pupillometry) will be further developed…
The main objectie of the study is to map the developmental trajectory of processing perceptual and social information in infants using fNIRS. In addition, with the measurement in 5 month-old children we aim to replicate previous research. The…
The main objective of this study is to determine the role of freeze-fight-flight reactions in the development and maintenance of PTSD symptomatology.
We hypothesize that perioperative ketamine will reduce cognitive decline in postoperative patients, in line with its analgesic and anti-inflammatory properties. There are no previous data available on the effect of ketamine on postoperative…
The primary objective is to study attachment in young children through skin-warming.
Predictive factors are needed to discriminate chemoradiotherapy responders from non-responders and to individualize the treatment regime. Various cytokines play a role in processes affecting tumour growth and metastasis. Furthermore, cytokines might…
The primary aim of this project is to examine the impact of heart failure on functional sympatholysis.
to compare in vivo total kidney 123I-MIBG uptake (by counts per pixel) by 123I-MIBG scintigraphy to direct ex vivo 123I-MIBG uptake of the flushed kidney as directly assessed with phosphor imaging.
Incidence of type 2 diabetes mellitus and cardiovascular disease in familial combined hyperlipidemia
To determine: 1) the incidence of type 2 diabetes mellitus in FCHL patients, normolipidemic relatives and their spouses2) the incidence of cardiovascular disease in FCHL patients, normolipidemic relatives and their spouses3) the prevalence of CESD…