171 resultaten
Antireflux surgery is one of the most common major operations performed in pediatric patients. Most studies on the outcome of antireflux surgery in children are limited to retrospective data, case reports or are based solely on symptoms. A…
we hypothesize that there is a link between gut microbiota composition and development of venous thrombosis.
Oral pazopanib once daily is safe and effective in advanced endometrial cancer for which no other therapies are available.
The first two exons of TRPV1 are deleted in the most common mutation found in cystinosis patients: A large 57 kb deletion. We aim to study TRPV1 expression in cystinosis patients both homozygous and heterozygous for this deletion.
Preoperative biliary drainage with metal stent in patients with resectable periampullary cancer results in less stent-related and drainage-related complications when compared to preoperative biliary drainage with plastic stents.
Breast cancer is one of the most common forms of female cancer worldwide. There are major limitations to the current imaging techniques that are used for diagnosing breast cancer. There is no single technique that combines an excellent sensitivity…
Evaluation of a population-based screening program for colorectal by repeated Fecal Immunochemical Test (FIT).
In the first 6 months Liraglutide affects weight more than CBT, but CBT provides weight maintenance after 12 months.
Clinically, children with syndromic craniosynostosis seem to have an increased risk of learning disabilities and behavioral problems in comparison with the general population.
We hypothesize that Moroccan-Dutch differ from native-Dutch in stress reactivity. This difference is not explained by group differences in known non-social risk factors for psychosis. Affirmative findings in the current study would support to the…
Postpartum urinary retention (PUR) is a complication with a varying prevalence, from 0.5 - 18%. For asymptomatic PUR, i.e. the ability to void but with a post residual volume (PVRV) of ≥150 ml, the estimation of prevalence is between 10-45%.…
The aim of the meta-analysis is to investigate the early predictive value of migration measured by RSA 2 years post-operatively for revision for aseptic loosening of the acetabular component in THA and to compose migration thresholds for safe and…
We hypothesize that higher distress levels will be associated with higher perceived need for and actual use of health care services, and with higher individual health care and work-loss related costs.
Develop a screening tool to identify children at risk of posttraumatic stress disorder after an accident.
EN - Unrelieved chronic pain represents a major problem for individual patients and is also a socio-economic burden for health services and the community at large. Although the etiology of musculoskeletal chronic pain following trauma is not well…
Moderate weight loss increases sensitivity to β2-AR-stimulated lipolysis in isolated adipocytes from subcutaneous adipose tissue biopsies.
Co-infection with either HIV or malaria may have a major impact on the immune response during bacterial sepsis. Current knowledge on the pathogenesis of sepsis indicates an unbalanced response to infection characterized by both excessive pro-…
We aim to validate Massive Parallel Sequencing in Primary Ciliary Dyskinesia (PCD) and identify novel disease causing mutations in the Dutch PCD population.
1. Breathprints, generated by an electronic nose, variate during mechanical ventilation; 2. Breathprints correlate with biological markers for oxidative stress and lung injury during mechanical ventilation.
Does addition of lenalidomide to chlorambucil and rituximab result in better response rates with acceptable toxicity.