10802 resultaten
We hypothesis that early surgical intervention results in less pain over the study period and is more cost-effective than the optimal current step-up practice.
Early laparoscopic cholecystectomy after endoscopic sphincterotomy for combined cholecystodocholithiasis, leads to less conversions as compared to laparoscopic cholecystectomy 6-8 weeks after sphincterotomy, and thus reduces morbidity and hosptal…
The hypotheses to be tested are that the outcome: 1. In arm B is better than in arm A; 2. Following PBSCT is better than following Cycle III chemotherapy.
The goal of the study is to: 1. Improve daily functioning in patients with schizophrenia; 2. To improve behavioral observation in psychiatric nurses; 3. To implement CAT in the usual treatment of patients with severe mental illness.
The aim of this study is making the work incapacity assessments of employees with a depression in the Netherlands more transparantly by using a Protocol Depression, developed by the Dutch Health Counsel. How can the Protocol Depression be…
shoulder muscle activation and movements in patients having a rotator cuff tear is affected compared to healthy volunteers, matched for age, with no cuff tear.
(1) PMTO, compared to Care As Usual (CAU), will result in statistically significant benefits in terms of: (a) parenting skills (b) parenting stress (c) child behavior problems (externalizing and internalizing) (d) child prosocial behavior (2)…
Continuing sulfonylurea in patients without good glycaemic control and using insulin and metformin, will diminish insulin secretion of beta-cells less than discontinuing sulfonylurea in these patients.
Compared to an online smoking cessation brochure, does participation in an online self-help smoking cessation program lead to: 1. A greater percentage successful quitters, three and six months after the start of the intervention; 2. A greater…
Resuscitation after birth with 30% oxygen reduces oxidative stress and is safe in preterm infants.
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1. Primary: A nocebo effect on cowhage-evoked itch will be induced through a conditioning with verbal suggestion paradigm, as measured by a larger difference in perceived itch during nocebo-associated and control test phase trials for the active…
Thoracic epidural anesthesia with local anesthetics produces intense sympathicolysis and protects the heart against ischemia during off pump coronary artery surgery
We hypothesize that ACP increases the wellbeing of persons with dementia somewhat, but that the effect is larger when the intervention matches the physician’s estimated readiness of the person with dementia or family caregiver to engage in the…
Brown adipose tissue (BAT) is thought to be involved in human glucose and lipid metabolism, however the mechanisms by which this adipose tissue is activated remain to be elucidated. Recent data in db/db mice have suggested that oral butyrate has…
Increasing age is associated with a decrease in step length, gait speed, and mobility. Gait speed predicts numerous clinical conditions, including independence and mortality. A variety of exercise interventions are highly effective in maintaining…
Surgical decompression of the nerves in the lower extremities in patients with diabetic symmetrical neuropathy improves symptoms.
Intradermal yellow fever vaccination with a reduced dose will induce a sufficient protective immunological response comparable to the response elicited by subcutaneous yellow fever vaccination.
Participants of the internet physical activity / self-management program will increase their level of physical activity and physical function compared to the control group.
Children with Osteogenesis Imperfecta type I and IV would benefit from a gradual trainingsprogram; increased exercise capacity and muscle strength could increase quality of life.