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We hypothesize that oral glucose intake and consequently the endogenous induced hyperinsulinemia will lead to insulin-induced microvascular dilatation in healthy normotensive subjects. Furthermore, we suggest that the insulin-mediated microvascular…
What is the effect of carbohydrate infusion on food choice, food intake, satiety, hormones, dependent on the time of day and segment of the small intestine?
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High-intensity stress reduces cognitive performance (visuo-spatial learning) both for immediate and delayed recall.
To investigate whether the clinical outcome is similar after the implantation of the Endeavor Resolute stent versus the XIENCE V stent (non-inferiority test).
- The level of psychotic reactivity differs between psychotic trait, state, and illness groups - Psychotic reactivity is mediated by biological reactivity in terms of dopamine and cortisol reactivity - The level of psychotic reactivity is…
ECT is effective as treatment of psychosis in patients suffering from clozapine resistant schizophrenia.
Nocturnal FFA levels are higher in obese insulin resistant subjects and are less sensitive to the FFA lowering effects of a â-receptor blocker.
In patients with non-insulin dependent type 2 diabetes, intensive, short term physical activity is associated with decreased blood glucose levels and number of cardiovascular complications. In patients who are insulin dependent however, the effects…
COPCA (Coping and Caring) intervention in infants at high risk for cerebral palsy will result in better functioning than Tradional Paediatric Therapy.
ADMA (asymmetric dimethylarginine) plasma concentrations are higher in persons with mild renal insufficiency compared to persons with normal kidney function. ADMA plasma concentrations are inversely proportional to renal perfusion and endothelial…
Multiple rounds of S(+)-ketamine infusions will give more profound and prolonged pain relief compared to a single infusion of S(+)-ketamine.
- Internet interventions without coach are less effective than those with a coach - The expected smaller outcomes weigh up to the advantages of a much simpler infrastructure, in clinical and economic outcomes
We hypothesise that one year compression therapy after DVT is equally effective as two years in the prevention of the post-thrombotic syndrome - in selected patients.
Case-management in ALS improves quality of life of ALS-patients and reduces the caregiver burden.
Investigate whether DWIBS is effective for colorectal cancer screening.
Walking, an aerobic exercise, has a positive effect on physical fitness, cognition, circadian rythm and mood
With usage of mesh material (Avaulta anterior) in the treatment of a cystocele >/ 2 with complaints a better anatomical result is achieved in comparence with the standard treatment (anterior colporraphy).
What is the effectiveness of Diclofenac compared to Paracetamol over a period of two weeks and if necessarily another two weeks (consistent with the Dutch guidelines for general practitioners) in new consulters with knee osteoarthritis in the…