45 resultaten
Hypothesis 1: Participants in both conditions (experimental and placebo) will show a reduction in gamble problem severity immediately post-intervention and at 3-and 6-month follow-ups. However, participants in the experimental condition will show a…
A. Rocuronium will induce impairment of carotid body function through blockade of cholinergic neurotransmission in carotid bodies resulting in a reduced or absent ventilatory response to isocapnic hypoxia. B. Sugammadex will completely restore…
We hypothesise that in the Subacromial Pain Syndrome (SAPS), a differentiation between primary peripheral (i.e. (peri)articular) and secondary pain due to altered processing of pain, i.e. central pain sensitisation, is needed. We further hypothesise…
The primary aim of the current research project is to establish whether the current Dutch vision screening in children aged 3-6 years old in PYHC can be improved by using plusoptiX, with regard to costs and screening performance.
We hypothesize that dietary nitrate supplementation improves muscle strength and muscle endurance performance.
Faecal transplantation from a healthy donor can restore the dysbiosis present in adolescents with refractory IBS, thereby inducing improvement of the IBS complaints.
Common colds have a significant impact on individuals, health care and economy. Functional food ingredients can reduce incidence, duration and severity of common respiratory tract infections in healthy elderly and adults. We hypothesize that test…
the correspondence between orosensation of sweetness and post-oral sensation of calories influences resting energy expenditure, cerebral blood flow and gastric emptying, and more specifically that the “not sweet enough” beverage, that contains more…
The aim of this study is to assess long term scar quality of deep dermal burns after debridement with hydrosurgical excision versus conventional tangential excision.
single denosumab injection has a beneficial effect on shortening time in contact cast and foot form preservation in DM subjects with an acute charcot foot
We hypothesize that 1) fasting duration may affect the central serotonin and dopamine systems, either centrally or indirectly through effects on peripheral input to the central nervous system, and 2) the effect of fasting may be changed in obesity.
The primary objective of the study is to investigate the role of expectations on conditioned pain modulation (CPM). Based on previous research it is expected that negative outcome expectations, induced by the verbal suggestion that a second painful…
Increased physical exercise of patients with a prostate carcinoma has a positive effect on quality of life.
We predict that the combination of the VR-GAIME and general aggression treatment will be more successful in reducing aggressive behavior.
Wireless Micro Current Stimulation (WMCS) accelerates wound healing in hard-to-heal chronic wounds compared to standard wound care.
We hypothesize that steering DBS will lead to a greater reduction of PD motor symptoms than ring-mode DBS. We will also separately measure the effect of the two types of DBS in people who have good response to ring-mode and those who don’t.
In this randomised, double-blind, placebo-controlled single centre study we propose to study the effect of duodenal infusion of single E. hallii treatment (administered via duodenal tube) on small intestinal gene expression, bacterial composition…
Anorexia nervosa (AN) is a psychiatric disease resulting in severely reduced food intake partly due to altered appetite/satiety balance resulting in very low BMI and the highest mortality rate of all mental illnesses1. Several forms of psychological…
We hypothesize that ketamine stimulates breathing and reverses opioid-induced respiratory depression.