156 results
To determine which phMRI technique/approach will give the largest signal change after oral 5-HT challenge. We will compare task-related (modulation) phMRI to resting-state (challenge) phMRI and within the task-related phMRI four different paradigms…
The aim of this project is to test the hypothesis that MDD patients with disturbances in anger/aggression regulation have more serotonin disturbances, as a trait marker for relapse, than MDD patients without disturbances in anger/aggression…
To investigate the effects of beclomethasone plus formoterol (in a single inhaler) versus single agents formoterol and beclomethasone dipropionate pMDI with HFA-134a propellant and placebo on the airway responses to allergen challenge. The primary…
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…
Suppression of SWS, without changing total sleep time, may affect total energy expenditure (TEE), activity induced energy expenditure (AEE), non-exercise activity thermogenesis (NEAT), endocrinological parameters and energy intake.
This study was therefore designed to determine whether cinnamon lower postprandial blood glucose, and insulin levels in subjects with type 2 diabetes or impaired glucose tolerance.
We hypoothesize that the effect that a single dose of montelukast has on exercise induced bronchoconstriction correlates with the effect it has after 8 weeks of treatment.
Het effect onderzoeken van acute verhoging van groeihormoon waardes op cognitief functioneren in gezonde mensen, en uitvinden of de relatie tussen groeihormoon en cognitie direct of indirect is. Doel van het onderzoek: We willen de acute effecten…
Autofluorescence endoscopy (AFE) has a higher sensitivity for the detection of colorectal adenomas in comparison with white light video endoscopy (WLE).
The primary objective of the present study is to assess efficacy of DBS in the nucleus accumbens for patients with refractory MDD. Secondary objectives are the evaluation of long term efficacy and tolerability of DBS for patients with therapy…
Non-invasive ventilation reduces the inflammatory response to exercise.
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The formula will be tolerated by at least 90% of the children with cow's milk allergy with a confidence interval of 95%.
Lipids are taken up by the heart when availability is high. High plasma concentrations of free fatty acids lead to increased lipid storage in the heart.
It is expected that dynamic leg and arm training and functional training with arm support can retard the progression of the disease at the level of muscle endurance and/or the functional abilities of the lower and/or upper extremity in boys who are…
In this study we have developed a vocational rehabilitation program based on the Chronic Disease Selfmanagement Program (CDSMP) of Stanford University. The CDSMP has been slightly modified to fit the needs of employees with a chronic disease. The…
Hepatic insulin sensitivity increase after dopamine depletion, with a-methylparatyrosine (AMPT).
Administration of a lipid emulsion consisting of long-chain triglycerides will induce insulin resistance due to increased DAG mass and subsequent activation of the PKC pathway in skeletal muscle. Infusion of a lipid emulsion consisting of medium-…
6MP treatment in pediatric ALL patients can be improved by developing a pediatric oral drinking solution of 6MP, assessing its bioequivalence, and -when successful- introducing the new formulation nationwide.
Smoking cessation after development of coronary heart disease improves prognosis more than any other treatment and prevents future cardiovascular diseases. This study aims to provide hospitalized coronary heart disease patients who smoke with proven…