81 results
Primary Objective: To show superiority of the novel fixtures compared to standard fixtures regarding stability of the implants measured as ISQ values.Secondary Objectives: 1. To compare the long time survival of the standard fixtures and abutments…
The goal of this study is to validate and interpret a new HRQOL instrument and to analyse commonly used outcome measurements (PGA, PtGA) in dermatology.
Our purpose is to establish whether the frequently observed absence of tumor regression in the presence of infiltrating T lymphocytes is due to a lack of T cell effector function or due to an inhibitory influence of the tumor microenvironment on T…
To assess validity and reliability of two pain observation scales in children with burns aged 0 to 4 years. Moreover, nurses will be asked to judge use-friendliness of the scales.After completion of the study, one of the scales should be used daily…
objective
To investigate whether fatigue is a side effect of etanercept.
The overall aim of the study is to investigate the Ponto wide implant considering; initial implant stability, stability over time, skin reaction and long term success when loaded at 3 weeks post surgery. Patients* quality of life improvements…
Client wishes to see if HPP-A is active in the transplant model of psoriasis
Primary objectivesTo study the relation between the physiological, microbiological and immunological status of the skin and the response to an external stimulus; to assess:• the relations between microbiome and/or immunology and the skin type;• the…
To develop and validate transplant models of vitiligo and atopic dermatitis for drug testing.
Is CMPX-2030 effective in the transplant model of psoriasis
1) Does FSAP activation in plasma of HAE patients contributes to bradykinin formation? 2) Study the inhibitory efficacy of c1-inhibitor towards kallikrein and FSAP towards bradykinin formation in a endothelial cell-based system. 3) test the efficacy…
The purpose of this study is to investigate how well a new dosage form of tildrakizumab is tolerated when it is administered to healthy volunteers. Tildrakizumab (also known as Ilumetri) is no new compound; it is already available on the market as a…
The aim of the project is to study the effect of GRTs on the synthesis and cytokine release in psoriasis lesions. Thisinformation can establish the right formulation and dose of GRTs for further research.
Collection of skin tissue and blood samples from patients with mild to moderate psoriasis for efficacy testing of a new compound in a humanized mouse model, and validation of the mouse model.
The aim of the project is to study the effect of ALPN test compounds on typical features of the chronic disease psoriasis. This information can establish the most effective compound with the right formulation and dose for further research (e.g. in…
The aim of the project is to study the effect of CDor and CDiv test compounds on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical research.
- Assess whether early markers (in blood and/or skin) can predict the clinical response to treatment (i.e. surface area of repigmented skin after 3 and 6 months of standard of care treatment).- Assess the relation between markers in blood, skin…
The aim of the project is to study the effect of INC1 and INC2 test compounds on typical features of the chronic disease psoriasis. This information can establish the most effective compound with the right formulation and dose for further research (…
o To test the linearity of the LSCI device (Perimed AB, Järfälla, Sweden) and LDI device (Moor Instruments, Devon, UK) in a wide range of blood flux valueso To compare arbitrary units of two different kinds of laser-based devices and to create a…