65 results
The goal of this study is to determine if off-pump CABG surgery is associated with better cerebral tissue oxygenation when compared with on-pump CABG. In addition, we would like to compare the results of two different monitors of brain tissue…
We will investigate the changes in mental performance using a validated computerize test battery of neuropsychological tests just before, three montns and one year after living kidney donation. Using visual and auditory inormation stimuli, these…
The aim of this project is to gain insight in which somatic, cognitive and psychosocialfactors contribute to preservation of functioning, in order to identify older people with potentialrisk of functional decline in an early stage and develop…
The main purpose of the proposed naturalistic pilot study is to compare postsynaptic DA receptor binding (reflecting synaptic DA concentrations) and brain Phe levels in PKU adults with lower blood Phe levels with PKU adults with higher blood Phe…
The primary goal of this project is to study whether children with ADHD differ from the normal population on the urinary and plasma levels of the AAA*s (tryptophan, tyrosine and phenylalanine) that are related to the functioning of serotonin and…
Our objective is to test the following hypotheses : - Hypothesis 1 (part 1 of the study): The stress reduction intervention has beneficial effects on subjective maternal emotional well-being, on objective maternal stress system measures (i.e., HPA-…
(1) to determine the psychiatric status (ADHD and ODD/CD) for the second time in participants from ADHD and control families about 5 years after the first assessment. The participants will be between 10 and 23 years of age now; (2) to determine the…
Primary objective:To determine the most important risk factors for falls in elderly people with mental retardation and to describe which of these factors may be modified by intervention/treatment, in order to prevent falls.Secondary objective:To…
To investigate whether impairments of shifting between response sets underlie motor freezing in PD and to investigate the efficacy and the neural mechanism by which MPH improves gait and cognition in PD patients with FOG.
The overall aim of the study is to enrich the database of the Dutch IMAGE samples with (1) structural magnetic resonance imaging (sMRI) and functional MRI (fMRI) data; (2) follow-up data of clinical status (ADHD symptoms and relevant comorbidities)…
Primary researchquestion:1. What are the differences in eye-hand coordination in patients with left or right hemisphere damage compared to healthy age-matched controls?Secondary research questions:2. What is the difference in eye-hand coordination…
The primary aim of this study is to identify the psychosocial determinants of stress (vulnerability) and cognitive complaints in breast cancer patients treated with adjuvant radiotherapy. The stress model of Taylor and Aspinwall will be used.
To investigate sleeping disorders in adults with ADHD, especially sleep onset disorders related to the circadian rhythm. Furthermore, the etiology (DNA) as well as possible additional chronobiological and general health variables will be addressed.
By restricting the inclusion on the fMRI studies to participants with deficits on a specific domain we hope to examine the unique neural mechanisms contributing to specific impairments. This will allow us to address the question whether…
1.To describe whether vascular lesions are more frequent in elderly heart failure patients compared to elderly patients with cardiovascular disease but no heart failure.2.To describe the association between these vascular lesions and executive…
The main objective of this study is to identify the incidence of POCD in adult patients under 50 years of age, who undergo major surgery
This study will be focused on the executive functioning of PD patients and the associations between effort, motor symptoms, depression and the executive functioning of PD patients. By investigating to what extent executive dysfunctions in PD are…
To determine the variability of cognitive features in NF1 and TSC in the absence of genetic variability.
Primary Objective: - to determine cognitive impairment in patients with severe renal failureSecondary Objective(s): - to determine to what extent this impairment improves after a kidney transplantation - to evaluate changes in uremic toxins after…
1. Study the BBB permeability in cSVD patients and compare it with healthy control subjects. 2. Examine the relationship between BBB permeability and cognitive function. 3. Examine the relationship between BBB permeability and the extent of…