306 resultaten
Het bepalen van de invloed van tDCS-parameters en een veelvoorkomende genetische mutatie in BDNF op motorisch leergedrag bij gezonde personen met behulp van de visuomotor adaptatiesnelheid en retentie.
Doel van het onderzoek is om bij gezonde mannelijke vrijwilligers het effect van vasten en vetrijke voeding te bestuderen op het metabolisme van paracetamol.
Belangrijkste doel van de studie is de optimale belichtingshoek en intensiteit bepalen voor het opwekken van niet-visuele responsies met behulp van blauwe LED verlichting in een bril.
Het primaire doel van het onderzoek betreft het effect van efedrine behandeling als toevoeging aan bestaande behandeling bij geïncludeerde patiënten met myasthenia gravis. Secundaire doelen zijn het effect in individuele patiënten, uitvoerbaarheid…
Het vaststellen van veranderingen in de kerntemperatuur onder remming van de PGE2 productie onder simultane blokkade van COX op centraal en perifeer niveau (paracetamol + ibuprofen) vergeleken met een controleconditie en met blokkade van COX op…
Different studies have shown that a hunter-gatherer type diet is effective in improving glucose regulation and lipid profile. I want to investigate if the hypothese that this type of diet also reduces the number of physical and psychological…
The present mode of (tonic) SCS is accompanied by paraesthesia in the area of stimulation. Recently, a new mode of SCS has been developed which makes it possible to apply spinal cord stimulation without paraesthesias. This mode is called burst…
Inhalation of once daily double dose of inhaled tobramycin targeted to the small airways by the Akita (1x 300 mg instead of 2x 150 mg) is more effective in reducing small airways obstruction compared with standard of treatment: twice daily…
Increasing age is associated with a decrease in step length, gait speed, and mobility. Gait speed predicts numerous clinical conditions, including independence and mortality. A variety of exercise interventions are highly effective in maintaining…
Oral sodium butyrate use in subjects with type 1 diabetes will lead to an altered innate immune system response, ultimately improving beta cell function and glucose regulation.
Primary objective: To determine the safety of once daily inhalation of the recommended daily dose of tobramycin with the Akita® and the PARI-LC® Plus nebulizer in patients with CF. Systemic absorption can be used as surrogate parameter for safety.…
The individual counselling intervention will significantly
Use of this walk-bike in daily life extends the range and everyday mobility of IPF patients, thereby decreases the level of dependency and social isolation, factors that are associated with quality of life. If, with this low-cost intervention, daily…
In the process of developing a serious game for testing patients’ level of myocontrol a part of the test needs to be validated. In a previous trial we found differences between several tests that need further inspection. The current study focusses…
We hypothesize that the circulatory and cardiac effects of TEA will be most pronounced during circumstances of increased sympathicotonus, which will be induced by an exercise test on a bicycle.
1. Methylphenidate (MPH) increases activation in task relevant areas and task performance 2. Hydrocortisone (HC) increases activation in task relevant areas and task performance 3. MPH + HC increase activation in task relevant areas, but might…
We hypothesize that inhalation of helium gas induces release of protective factors in the blood, which can be used to protect different cell types against ischemia/reperfusion injury.
The main objective of the FitSupport study is to include 3000 supporters of the soccer clubs into the intervention through two different inclusion strategies; one digital and one personal recruitment strategy. These participants will be divided in…