28 resultaten
In adult congenital heart disease patients with exercise-induced pulmonary arterial hypertension, treatment with bosentan lowers the mean pulmonary arterial pressure, which may result in improvement of the cardiopulmonary circulation,…
Using low field stimulation on two brain regions simultaneously, we aim to specifically alter the connectivity between one or more pairs of brain areas.
Hypotheses: 1. That there will be a change in the negative sense in sensory stimulus processing after 2 weeks and possibly up to 3 months after anaesthesia as measured with I/T SP; 2. That there is a relation between postoperative changes as…
Intranasal insulin will improve development and behaviour in children with Phelan-McDermid syndrome.
Healthy volunteers and patients with a high variability in pain scores have a high probability to experience pain relief from alfentanil opposed to volunteers and patients with a low variability in pain scores.
Motor cortex or cerebellar tDCS(transcranial Direct Current Stimulation) will enhance motor skill learning in heatlhy subjects and chronic stroke survivors. Stimulating the motor cortex will result in an increase in offline learning, whereas…
1. The deafferentiation during spinal anesthesia changes the connectivity in resting-state networks in healthy volunteers; 2. The deafferentiation during spinal anesthesia changes pain perception and has sedetive effects.
The addition of milk protein hydrolysate and tryptophan rich proteins and/or decreasing stomach emptying rate in combination with increased satiety, will improve sleep onset and efficiency significantly as compared with the current available growing…
Patients administered perioperative reversed local infiltration of ropivacaine will have lower pain scores, a faster rehabilitation, and lower cumulative consumption of (opioid-) pain medication postoperative, when compared to patients administered…
To analyze the additional benefits of nebulization with a solution of NaCl or salbutamol after exercise by elite skaters in dry air in comparison to elite skaters not nebulising (controls). Reduced decrease in FEV1 after exercise by the verum group…
The present study will investigate: 1. Whether drug-related cues activate the same neural networks as does the administration of the drug itself; 2. The implicit and explicit associations of alcohol and cannabis users; 3. The effect of acute doses…
The hypothesis is that patients undergoing an axillary lymph node dissecion with preserving of the lymph nodes and vessels of the upper extrimity (ALND-ARM) have less postoperative complications compared to patients undergoing a standard axillary…
The current study will focus on the effects of an intensive programme of exposure to prism adaptation (i.e. daily exposure during two weeks) and whether more permanent changes in spatial awareness can be objectified. To assess the effects of prism…
The scientific hypothesis of the present study is that oral hygiene care with a 0.05 % chlorhexidine-containing solution, compared to oral hygiene care with a placebo, reduces the incidence of pneumonia in physically-impaired care home residents…
Objective of this study is to assess the sensitivity of performance in a number of widely used tests for measuring driver impairment to the dose-effects of alcohol.
Primair: veiligheid en verdraagbaarheid van belimumab bij kinderen van 5-17 jaar met SLE.Secundair: PK, werkzaamheid, kwaliteit van leven.
Wij vermoeden dat bij mensen met multiple sclerose de verwerking van energiestoffen zoals suikers (energiemetabolisme) niet optimaal verloopt in de hersenen. Dit zou volgens ons een verklaring kunnen bieden voor de progressieve achteruitgang van de…
- Identificeren via welke hersenmechanismen en gedrag oxytocine invloed heeft op de gedragen die mensen vertonen in een communicatie situatie
De doelstellingen van deze studie zijn het bepalen van de veiligheid en doeltreffendheid van IW-9179 toegediend aan patiënten met functionele dyspepsie (FD), met of zonder gelijktijdig toegediende protonpompremmer (PPI).
Het primaire doel: De hypothese te toetsen dat het oraal geven van risperidon (uitgaande van 0.01 - 0.04 mg/kg/d) voor een periode van 12 weken superieur is aan een placebo, om de gedrags symptomen te verminderen die geassocieerd zijn met volgens de…