391 resultaten
Anxiety disorders and depression are common illnesses that have a negative impact on everyday functioning, cause great suffering, and entail both high care costs and loss of production. Recognition, diagnosis and stepped care allocation of treatment…
We hypothesize that subjects (Asian or Caucasian) with the COMTH allele (Val/Val polymorphism) respond stronger to the GT treatment than subjects with the COMTL allele (Met/Met polymorphism), consequently have an increased EE and that the genetic…
The use of the BITSEA as screening tool compared to Kort Instrument voor Psychologische en Pedagogische Probleem Inventarisatie (KIPPPI-2 – a screening instrument for psychological and developmental problems designed for 2 year olds), results in…
1. What is the effect of the training program on physical health, depressive symptoms, cognitive and executive functions of people with dementia in comparison with care-as-usual? 2. What is the effect of the training program on physical health,…
It is hypothesized that in the population of frequent cannabis users, cross tolerance will have developed for the effects of alcohol, and that therefore the behavioral effects after alcohol will be less when given in combination with cannabis.
Activation of SIRT1 (silent information regulator transcript) results in inhibition of inflammation in humans.
The effect of stepping down asthma therapy in clinically stable children on exercise induced asthma.
We hypothesized that in a subgroup of patients EIBH would improve after the cessation of LABA.
To compare the differences in duration of delirium in delirious patients receiving anti-psychotic therapy + melatonin or anti-psychotic therapy + placebo.
To evaluate the clinical and diagnostic ability of the micro TEE transducer, the smallest multiplane TEE in the world, in pediatric patients greater than 2.5 kg undergoing cardiac surgery to provide data on imaging quality.
Inspiratory Muscle Training during primary rehabilitation will improve respiratory function in Spinal Cord Injury. Respiratory Muscle Training will decrease the risk for long-term respiratory symptoms and complications in persons with spinal cord…
Development of early-onset dementia (EOD) is very radical and disabling for both patient and family, due to the still prominent role of the patient in society. Except for knowledge on cognitive disorders not much is known about other disabling…
Approximately 2% of the Dutch elderly population suffers from a major depressive disorder (MDD). Due to a depressed mood and a diminished interest in nearly all activities, MDD has serious consequences for daily living (e.g. withdrawal from social…
Shoulder pain is related to somatosensory and nociceptive changes in the acute phase after stroke. These changes may indicate the involvement of specific mechanisms (nociceptive, neuropathic) of post-stroke shoulder pain. Changes may either precede…
Whether antibiotic guidance by procalcitonin measurements are able to reduce antibiotic usage and duration in Dutch intensive care units.
Hemodynamic optimization during and after colorectal surgery results in improved intestinal perfusion, sustained intestinal barrier and improved postoperative recovery.
We hypoothesize that the effect that a single dose of montelukast has on exercise induced bronchoconstriction correlates with the effect it has after 8 weeks of treatment.
Presence of postural instability and gait dissorder PIGD (gait disorders, balance impairment, falls, fal-related injuries and FOG) are an important and disabling feature of idiopathic Parkinson’s disease (PD) where the level of functional ability is…
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…
1. In Barrett Esophagus (BE), probe-based laser endomicroscopy (pCLE) provides better correlation with the histological diagnosis compared to detailed inspection with Narrow Band Imaging (NBI), reducing the high rate of false-positive findings with…
Detection of chronic pain in adolescents by self-report combined with advice from a school nurse will be efficient and effective.