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Objectives Primary: To examine the effects of regular glucose lowering treatment on inflammatory markers in type 2 Diabetes Mellitus Secondary: To identify markers/fingerprints that predict the response of a patient to glucose lowering therapy in…
Authors hypothesized that the physical extracorporeal shock wave (ESW) stimulation will decrease the resting muscle activity of paralysed forearm muscles, reducing the degree of spasticity in surface electromyography examination as well as Modified…
This study will explore the feasibility of post-transplant panobinostat combined with decitabine after reduced intensity conditioning (RIC) alloHSCT in patients with (very) poor-risk AMLor RAEB with IPSS >= 1.5 (AML/RAEB). While recent…
In Gabon, antimalarial drugs are widely available in both the private as well in the public sector and often self-prescribed (correctly and incorrectly) for the many febrile episodes attributed to malaria. Insufficient facilities to check the…
18F-FDHT PET/CT is expected to be a predictor of response in patients with metastasized castration-resistant prostate cancer to be treated with enzalutamide
This is a clinical trial in the home environment of 60 epilepsy patients to investigate the sensitivity and positive predictive value of a multimodal sensor system (‘LivAssured’) for the detection of nocturnal motor seizures.
The aim of the study is: (1) observational, i.e., to assess and describe the responses of patients and volunteers to a variety of different stimulation paradigms; (2) diagnostic, i.e., to assess whether specific tests are possibly diagnostic for…
We expect an improvement in psychological flexibility and a decrease in pain interference in daily life or in fatigue. Furthermore, we expect a decrease in depression and anxiety symptoms.
To find out if intravenous MSC is a safe treatment for children with therapy-resistant JIA
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Use of exercise instructions by means of a tablet and monitoring by means of a necklace-worn motion sensor is beneficial for adherence in home-based exercise programs for older adults.
Whole blood thrombin generation measurement is comparable to plasma thrombin generation in clinical setting.
The objective of the proposed study is the intraoperative detection of tumor tissue of peritoneal carcinomatosis of colorectal origin by using a near-infrared fluorophore, 800CW, conjugated to bevacizumab resulting in a bevacizumab-IRDye800CW…
This study aims to assess the feasibility of a dose-adjusted MPV scheme in patients >= 75 years of age and to assess the value of geriatric assessments to predict both feasibility and efficacy.
Our primary hypothesis is that IRE will add a maximum of 28% clinically relevant complications, defined as Clavien-Dindo score 3 or higher, to the current 28% of complications associated with palliative treatment.
We hypothesize that patients with type 2 diabetes and first-degree realtives of patients with type 2 diabetes are characterized with a diminished branched-chain amino acid oxidative capacity
1. MBSR will reduce symptoms of distress, anxiety and depression 2. MBSR will reduce fatigue, pain and sleep disturbance 3. MBSR will improve coping with cancer
To reduce treatment-related toxicity in patients with localized prostate cancer, focal treatment is warranted. This can be achieved with MRI guided high-dose-rate brachytherapy. We expect that a single dose of 19 Gy to the tumour volume will be of…
The aim is to evaluate molecular assays for the detection and quantification of bacterial DNA in blood from patients with bacteraemia.