141 resultaten
The self-help intervention Happy@Work will reduce symptoms of depression. The self-help intervention Happy@Work will be cost effective.
An intervention consisting of a set of specific fatigue reducing and health enhancing advices will lead to less fatigue and sickness absence in airline pilots. Following the intervention and the accompanying advices will lead to pilots reporting…
A constant Hb concentration will improve the quality of life of patiënts with a chronic need for bloodtransfusions.
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The aims of this study are twofold: 1. Examine the effectiveness of the web-based CBT self-help intervention for MS-patients with depressive symptoms; 2. Compare characteristics of symptoms of depression and anxiety, quality of life and perceived…
The aim of this study is to investigate the effectiveness and the cost-effectiveness of the individual CBT program the “D(o)epressie cursus” by means of the following hypotheses; 1. Is the individual CBT program the “D(o)epressie cursus” more…
To evaluate the impact of three different implementation strategies for implementing IBSM in current clinical practice, we have proposed the following three hypotheses: 1. Hypothesis 1 (Reach): More general practices will participate in IBSM in the…
Patients treated with chemotherapy are at higher risk of influenza infection and mortality and morbidity are higher compared to healthy adults. Vaccination against the influenza virus can prevent these complications. Although vaccination in oncology…
The fetus is protected from maternal immune responses through various mechanisms such as lack of expression of classical HLA class I and class II molecules, inhibitory T cell, costimulatory molecules, NK cells, complement regulatory proteins by…
Which of two strategies for early detection of depression in primary care performs best, i.e. results in higher number of identified depressions. The two strategies are: 1. Active case finding of high risk patients by a nurse practitioner; 2.…
The primary objective is to compare the pharmacokinetic profile of tacrolimus after rectal and sublingual administration with oral administration.
The addition of a Functional Capacity Evaluation to a cognitive behavioral intervention will improve work ability, quality of life and self efficacy.
1. Muscle ultrasound is capable to detect dermatomyositis and polymyositis in suspected patients; 2. Muscle ultrasound is capable to detect improvement of structural muscle changes induced by treatment; 3. Muscle ultrasound is capable to detect…
AN-PEP helps to digest gluten in vivo.
The objectives are firstly that the Tackling Teenage training increases knowledge, skills and confidence of young people with autism spectrum problems (ASP) , and that inappropriate sexual behavior decreases and secondly that the (sexual)…
Artificial dynamic lightening can positively influence the sleep/wake cycle and reduce the disturbance of the circadian rhythm due to hospitalization.
Necessity: A study on chronic pain in persons with Down syndrome is clinical relevant for 5 reasons: 1. The neuropathology of Down syndrome without and with dementia affects pain-related gray and white matter, which may alter pain experience; 2. The…
We hypothesize that addition of low-dose haloperidol prophylaxis (1.0mg twice-daily) on top of the existing standard of care reduces in-hospital delirium incidence, severity and duration in a general patient population, age 70 years or over, who are…
Compared to usual care, a new perioperative care program will improved recovery and accelerated resumption of (work)activities. Resumption of work contributes significantly to QOL and will prevent disability due to general and mental health problems…
The OptiScanner provides accurate blood glucose levels in critically ill patients.