134 resultaten
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
Therapeutic drug monitoring is effective in optimizing treatment with tobramycin and reduces side effects.
We hypothesize that monomeric and oligomeric flavanols (MOF) have a beneficial effect on renal-endothelial function in the dietary management of T2D, as reflected by improvement of AER and renal-endothelial biomarkers.
Microspirometry result in a higher proportion of diagnostic spirometric assessment to objectify the existence or absence of a chronic airflow obstruction within 3 months after a patients at risk for COPD visited the GP compared to usual care.
The primary objectives of this project are: - Identify neural correlates and behavioural measures that underlie cognitive processes that perpetuate CFS symptoms - Identify neural mechanisms of change that mediate successful CBT.
This study will explore the feasibility of post-transplant panobinostat combined with decitabine after reduced intensity conditioning (RIC) alloHSCT in patients with (very) poor-risk AMLor RAEB with IPSS >= 1.5 (AML/RAEB). While recent…
To assess the effect of an Amino Acid based Formula (AAF) with synbiotics on the balance of major constituents of the gut microbiota, specifically Bifidobacteria vs. Clostridial groups.
The Solace European Confirmatory (SOLECT) Trial is designed to determine whether the Solace Bladder Control System is safe and effective for the treatment of Stress Urinary Incontinence (SUI) in adult females.
In Gabon, antimalarial drugs are widely available in both the private as well in the public sector and often self-prescribed (correctly and incorrectly) for the many febrile episodes attributed to malaria. Insufficient facilities to check the…
The percentage of successful PIV insertions at the first attempt in newborns will increase with the Veinviewer® and/or Astodia®, two vascular imaging devices
There are no effective interventions to prevent dehydration of elderly people available. Therefeore the RPHS West-Brabant, together with the Gneral Practice de Keen, decided to develop and analyse the efffect of an education strategy. Besides that…
Delivery of a generic MBSR training to patients who visit a memory clinic with cognitive complaints, and who show no clinical signs of a cognitive disorder, is feasible.
We expect an improvement in psychological flexibility and a decrease in pain interference in daily life or in fatigue. Furthermore, we expect a decrease in depression and anxiety symptoms.
This study primarily aims to explore changes in physical activity pattern and energy expenditure in head and neck cancer patients, during and after treatment with surgery with or without (chemo)radiation. The following primary null hypotheses will…
Think different: effectiveness of an online training for children with obsessive-compulsive disorder
The aim of the present study is to improve treatment for children with OCD by adding an online Cognitive Bias Modification-Interpretation (CBM-I) training as a pre-treatment to cognitive behavioural therapy (CBT). CBM-I is compared with a waitlist…
People with aphasia have problems with communicating. Because communication is very important in the society, these group suffers from a smaller social network, diminished social participation and as a result of this, loneliness, a loss of autonomy…
The aim of the current study is to test whether online training of a positive attentional bias or positive interpretation bias is successful in increasing resilience, reducing internalizing symptoms and preventing clinical disorders (anxiety/…
We hypothesize that daily oral administration of increasing dosages of Eubacterium hallii, an anaerobic intestinal bacterial strain, can exert beneficial effects on insulin sensitivity and liver fat.
The present study aims at the improvement of the treatment of children with PTSD by examining the effectiveness of a brief intensive exposure therapy (IET) for children with PTSD using a multiple baseline design (patients are randomly assigned to…
It is expected that acute challenges with cocaine will induce two opposing effect on creativity. That is, cocaine will increase mood leading to enhancement in divergent but not in convergent thinking.