498 resultaten
Background: Injury rate and injury severity of elderly cyclists due to self-induced cycle accidents increase with age. Starting at the age of 55 years, injury risk increases with a factor 4 at the age of 75 years. Injury mechanisms such as slippery…
-Six weeks of treatment with a supplementary low dose of clonidine to the current medical treatment of clozapine resistant patients will effectively reduce symptom severity and cognitive impairments in therapy resistant schizophrenia patients -…
The combination of breast surgery, radiotherapy and chemotherapy have a profound effect on the deep myofascial level and in turn, they create a vicious circle of adhesions and lack of mobility and pain in muscles, fasciae and joints around the…
Combination therapy with telaprevir/ ribavirin is as effective as the current standard of care with peginterferon-alfa/ ribavirin for the treatment of acute Hepatitis C in HIV-infected individuals.
A proportion of patients with juvenile idiopathic arthritis with minimal disease activity can remain in a state of minimal disease activity with a lower dose of etanercept than the standard dose or even without etanercept.
Our hypothesis is that custom made insoles and a home-based exercise program would be superior to a home-based exercise program alone at 12 weeks follow-up.
In adult congenital heart disease patients with exercise-induced pulmonary arterial hypertension, treatment with bosentan lowers the mean pulmonary arterial pressure, which may result in improvement of the cardiopulmonary circulation,…
Casein ingested within a normal milk matrix results in a more rapid digestion and amino acid absorption, resulting in greater amino acid availability and post-prandial muscle protein accretion as compared to the ingestion of isolated casein (…
We hypothesize this difference is due to differences in the mechanisms by which the individuals can withstand and/or adapt to the stress conditions applied in the clinical model and that these mechanisms are of key importance in our ability to…
Vitamin D supplementation reduces the incidence of delayed union in fracture patients with a vitamin D insufficiency, compared to placebo.
Our primary outcome is to change knowledge, attitude and managing skills of prison staff. We hypothesis that the elearning module will contribute to improve knowledge, attitude and skills
The effectiveness of school-based ('Op Volle Kracht') and computerized ('SPARX') depression prevention programs will be tested in a Dutch sample of adolescent girls with elevated depressive symptoms. The programs will be tested…
Is a prevention program, based on principles of health behavior change, education about playing-related musculoskeletal disorders and postural training, more effective in preventing and/ or reducing disabilities from musculoskeletal complaints in…
We hypothesise that the new MRI protocol will be superior to the previous protocol at calculating lung volumes and central airways dimensions, and subsequently improve the detection and quantification of TA in both CF and asthma disease pathologies.
The hypothesis is, when adolescents are screened for problems at an early stage and do get help, they will be less absent from school and will have less psychosocial problems.
Prevention of parastomal hernia with a prosthetic mesh in a laparoscopic constructed end-colostomy .
The use of a low weight polypropylene mesh(PPM) in a sublay position reduce the incidence of parastomal hernia in laparoscopic stoma formation.
The goal of this intervention is: 1. To improve the support for successful social participation for adolescents with a visual impairment 2. To develop Mentor Support for the improvement of social participation in adolescents with visual impairments…
A systems biology approach is an hypothesis free study that looks at multiple layers within one patient (genome, epigenome, proteome, metabolome)
The aim of the study is to compare the efficacy of per-oral endoscopic myotomy (POEM) to the efficacy of pneumodilation as the initial treatment of symptomatic idiopathic achalasia. It is hypothesized that POEM has a higher long-term efficacy than…
The primary objective of this study is to analyse whether preventive hamstring exercises (Nordic Hamstring Curl) can reduce injury incidence in Dutch elite amateur soccer players. The secondary objective of this study is to analyse whether…